Phospho-FAK (Y861) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-FAK (Y861)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat, monkey
Isotypen/a
Formataffinity purified
Size0.02 mL, 0.06 mL, 0.12 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionBackground/Introduction: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubuleinduced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Immunogenn/a
Other Names[PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK]
Gene, Accession #[FAK], Gene ID: 5747, NCBI: NP_001303271.1
Catalog #MBS2536151
Price$110, $150, $225
Order / More InfoPhospho-FAK (Y861) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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