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Antigenic Specificity | VSIG4 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. No VSIG4 expression appears to be present in T and B cells. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also |
Immunogen | Immunogen: Recombinant Human VSIG4 protein Buffer: PBS with 0.05% sodium azide, 30% glycerol |
Other Names | [CRIg; Protein Z39Ig; V set and immunoglobulin; domain containing 4; VSIG4; Z39IG] |
Gene, Accession # | [VSIG4], Gene ID: 11326, UniProt: Q9Y279 |
Catalog # | MBS2543686 |
Price | $295, $475, $735 |
Order / More Info | VSIG4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |