Human TAR DNA-binding protein 43 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman TAR DNA-binding protein 43
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionDNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR.
ImmunogenImmunogen: Recombinant human TARDBP protein (1-260aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-102127 / sc-292299
Other Names[TDP-43; TARDBP; TDP43], [TARDBP; TARDBP; ALS10; TDP-43; TDP43; TDP-43]
Gene, Accession #[TARDBP], Gene ID: 23435, NCBI: NP_031401.1, UniProt: Q13148
Catalog #MBS1497439
Price$120, $160
Order / More InfoHuman TAR DNA-binding protein 43 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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