Human Tollip Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Tollip |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 100ug/200ul |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human Tollip; Does not react to TLR2, TLR4, TLR6, TLR7, TLR8 and TLR10 recombinant proteins. Tollip, Toll-interacting protein, is a 30 kDa adaptor protein that is a component of the signaling pathway of IL-1 and Toll-like receptors. Tollip forms a complex with IRAK (IL-1 receptor associated kinase) and inhibits IL-1-induced signaling by blocking IRAK phosphorylation. The co-recruitment of MyD88 triggers IRAK autophosphorylation, which in turn leads to the rapid dissociation of IRAK and Tollip. Tollip is also an important signaling component of the TLR2 and TLR4 pathways by playing an inhibitory role in TLRmediated cell activation. Tollip also associates with Tom1 (target of Myb1) forming a complex which regulates endosomal traf |
| Immunogen | Immunogen: Recombinant Tollip Storage Buffer: 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. |
| Other Names | [toll-interacting protein isoform 1; Toll-interacting protein; toll-interacting protein; toll interacting protein] |
| Gene, Accession # | Gene ID: 54472, NCBI: NP_061882.2, UniProt: Q9H0E2 |
| Catalog # | MBS4152643 |
| Price | $445 |
| Order / More Info | Human Tollip Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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