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Antigenic Specificity | Human CENPU / MLF1IP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: A BLAST analysis was used to suggest cross-reactivity with MLF1IP protein from human, chimpanzee (98%), horse (72%), bovine (69%), dog (65%), mouse (56%), rat (55%) and chicken (47%) sources based on homology with the immunizing sequence. Myeloid leukemia factor-1 (MLF1) Interacting protein, also known as PBIP1, is a novel gene that encodes a putative transcriptional repressor. It is localized to human chromosome 4q35.1, is expressed in both the nuclei and cytoplasm of cells, and is a novel substrate for polo-like kinase (PLK1). Phosphorylation by PLK1 regulates the PLK1-MLF1 interaction and localization to the kinetochores promoting proper chromosome segregation. |
Immunogen | Immunogen Description: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a 418 residue recombinant protein corresponding to the carboxy terminal end of human MLF1IP protein. |
Other Names | [CENPU / MLF1IP (C-Terminus) IHC-plus; CENPU; CENP-U; CENP50; CENPU50; Centromere protein U; ICEN24; KLIP1; Polo-box-interacting protein 1; MLF1-interacting protein; CENP-50; Centromere protein of 50 kDa; MLF1 interacting protein; MLF1IP; PBIP1; Human CENPU; MLF1IP], [MLF1IP] |
Gene, Accession # | [CENPU], Gene ID: 79682, NCBI: NP_078905.2, UniProt: Q71F23 |
Catalog # | MBS248167 |
Price | $530 |
Order / More Info | Human CENPU / MLF1IP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |