MLL2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | MLL2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: MLL2 antibody detects endogenous levels of total MLL2. Function: Histone methyltransferase. Methylates 'Lys-4' of histone H3 (H3K4me). H3K4me represents a specific tag for epigenetic transcriptional activation. Acts as a coactivator for estrogen receptor by being recruited by ESR1, thereby activating transcription.Subunit Structure: Component of the MLL2/3 complex (also named ASCOM complex), at least composed of KMT2D/MLL2 or KMT2C/MLL3, ASH2L, RBBP5, WDR5, NCOA6, DPY30, KDM6A, PAXIP1/PTIP, PAGR1 and alpha-and beta-tubulin. Interacts with ESR1; interaction is direct.Similarity: LXXLL motifs 5 and 6 are essential for the association with ESR1 nuclear receptor. Belongs to the class V-like SAM-binding methyltransferase sup |
| Immunogen | Immunogen: A synthesized peptide derived from human MLL2 Subcellular Location: Nucleus. Tissue Specificity: Expressed in most adult tissues, including a variety of hematoipoietic cells, with the exception of the liver. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (83%), Dog (100%) |
| Other Names | [AAD10; ALL1 related gene; ALL1-related protein; ALR; CAGL114; Histone-lysine N-methyltransferase MLL2; KABUK1; Kabuki make up syndrome; Kabuki mental retardation syndrome; KMS; KMT2B; KMT2D; Lysine N methyltransferase 2D; Lysine N-methyltransferase 2B; MLL2; MLL2_HUMAN; MLL4; Myeloid/lymphoid or mixed lineage leukemia 2; Myeloid/lymphoid or mixed-lineage leukemia protein 2; TNRC21; Trinucleotide repeat containing 21] |
| Gene, Accession # | [MLL2], Gene ID: 8085, NCBI: NP_003473.3, UniProt: O14686 |
| Catalog # | MBS9609963 |
| Price | $240, $280 |
| Order / More Info | MLL2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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