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Antigenic Specificity | Human CD106 (VCAM-1) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/200ul |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human CD106/VCAM-1. CD106, also known as INCAM-1, is a 100-110 kDa vascular adhesion cell adhesion molecule-1 (VCAM-1) that is member of the immunoglobulin superfamily. CD106 is expressed predominantly on cytokineactivated vascular endothelium but has also been identified on interfollicular dendritic cells, some macrophages and bone marrow stromal cells. Endothelial CD106 binds the integrins beta4beta1 (CD49d/CD29, VLA-4) and beta4beta7 and contributes to extravasation of lymphocytes, monocytes, basophils and eosinophils (but not neutrophils) from blood vessels, particularly at sites of inflammation. Unlike the beta2 integrins, the CD106-VLA-4 interaction can mediate both the initial tethering and rolling of lymphocytes on endo |
Immunogen | n/a |
Other Names | [CD106 VCAM-1] |
Gene, Accession # | [CD106] |
Catalog # | MBS4152181 |
Price | $445 |
Order / More Info | Human CD106 (VCAM-1) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |