THEM4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTHEM4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionThe additional higher molecular weight bands seen in the immunoblot may represent post-translationally modified TMEM4. THEM4 Antibody: THEM4, also known as CTMP, binds specifically to the carboxy-terminal regulatory domain of PKB/Akt at the plasma membrane and acts as a negative regulator, reversing the phenotype of v-Akt-transformed cells. Hypermethylation of the THEM4 promoter and transcriptional downregulation of the gene has been reported in multiple glioblastomas, suggesting that epigenetic regulation of THEM4 may play a role in the progression of this cancer. Bioinformatic analysis, confirmed by in vitro testing, indicates that THEM4 is a broad-range, high activity acyl-CoA thioesterase. Recent reports have also indicated that TMEM4 i
ImmunogenImmunogen: THEM4 antibody was raised against an 18 amino acid synthetic peptide near the center of human THEM4. Buffer: THEM4 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[THEM4; CTMP; CTMP; Acyl-coenzyme A thioesterase THEM4; Carboxyl-terminal modulator protein; Acyl-CoA thioesterase THEM4; thioesterase superfamily member 4], [THEM4; THEM4; CTMP; CTMP; Acyl-CoA thioesterase THEM4]
Gene, Accession #[THEM4], Gene ID: 117145, NCBI: NP_444283, UniProt: Q5T1C6
Catalog #MBS150493
Price$375
Order / More InfoTHEM4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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