Mouse CD45R/B220 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD45R/B220 |
| Clone | [RA3.3A 1/6.1] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgM |
| Format | unconjugated |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD45, also known as leukocyte common antigen (LCA), B220, and T200, is a 180-2CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Faslpr and MRL-Fasgld mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate fo |
| Immunogen | n/a |
| Other Names | [Mouse CD45R/B220; B220; CD45; GP180; LCA; T200] |
| Gene, Accession # | [CD45R/B220], Gene ID: 19264, NCBI: NP_001104786.2, UniProt: P06800 |
| Catalog # | MBS2553973 |
| Price | $75, $90 |
| Order / More Info | Mouse CD45R/B220 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Barclay A, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Trowbridge IS, et al. 1993. Annu. Rev. Immunol. 12:85. 3. Kishihara K, et al. 1993. Cell 74:143. 4. Pulido R, et al. 1988. J. Immunol. 140:3851. |
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MYBIOSOURCE INC.
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