KAI1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-KAI1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | KAI1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | KAI1 was initially identified from a T-cell activation study as a four-transmembrane protein that plays an accessory role in T-cell activation, and was later determined to act as a cancer metastasis suppressor gene. This protein is ubiquitously expressed at moderate to high levels in most tissues, but its expression is downregulated during tumor progression. The loss of KAI1 and p53 is associated with poor survival for prostate and other cancer patients. Recently, KAI1 was found to interact with DARC, the Duffy antigen for chemokines using a yeast two hybrid screen. It is thought that tumor cells dislodged from the primary tumor and expressing KAI1 interact with DARC proteins expressed on vascular cells, transmitting a senescent signal to t |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 15 amino acid peptide from near the carboxy terminus of human KAI1. |
| Other Names | [CD82 antigen, tetraspanin-27, Tspan-27, suppressor of tumorgenicity-6] |
| Gene, Accession # | [KAI1], Gene ID: 3732, NCBI: NP_002222 |
| Catalog # | MBS9411544 |
| Price | $320 |
| Order / More Info | KAI1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies