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Antigenic Specificity | SGCA |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | mouse, rat. predicted to work with: human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Alpha-sarcoglycan(SGCA) detection. Tested with WB in Human;Mouse;Rat. Background: Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: E Coli-derived human SGCA recombinant protein (Position: Q24-H387). Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA. Ig Type: Rabbit IgG |
Other Names | [Alpha-sarcoglycan; 50 DAG; 50 kDa dystrophin associated glycoprotein; 50 kDa dystrophin-associated glycoprotein; 50DAG; 50kD DAG; 59kDa; A2; adhalin; ADL; Alpha SG; Alpha-sarcoglycan; Alpha-SG; Asg; DAG2; DMDA2; Dystroglycan 2; Dystroglycan-2; LGMD2D; sarcoglycan, alpha (dystrophin-associated glycoprotein); SCARMD1; Sgca; SGCA_HUMAN; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)], [SGCA; SGCA; ADL; DAG2; 50DAG; DMDA2; LGMD2D; SCARMD1; adhalin; ADL; DAG2; Alpha-SG; 50DAG] |
Gene, Accession # | [SGCA], Gene ID: 6442, NCBI: NP_000014.1, UniProt: Q16586 |
Catalog # | MBS177974 |
Price | $280 |
Order / More Info | SGCA Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein). 2. McNally EM, Yoshida M, Mizuno Y, Ozawa E, Kunkel LM (Nov 1994). Human adhalin is alternatively spliced and the gene is located on chromosome 17q21. Proc Natl Acad Sci U S A 91 (21): 9690-4. |