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Antigenic Specificity | AKT (Pan) |
Clone | [5A11-C9-G6] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, monkey |
Isotype | IgG2b |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation (By similarity). General protein kinase capable of phosphorylating several known proteins. Phosphorylates TBC1D4. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). Plays a role in glucose transport by mediating insulin-induced translocation of the GLUT4 glucose transporter to the cell surface. Mediates the antiapoptot |
Immunogen | Immunogen: Purified recombinant human Akt1 protein fragments expressed in E Coli. |
Other Names | [AKT1; AKT1_HUMAN; AKT2; AKT3; PKB alpha; PKB; PKB beta; PKBalpha; PRKBA; PRKBB; PRKBG; Protein kinase B; Protein kinase B beta; Protein kinase B gamma; Proto-oncogene c-Akt; RAC alpha; RAC; RAC gamma; RAC PK alpha; RAC PK beta; RAC PK gamma; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; STK2] |
Gene, Accession # | [AKT], Gene ID: 207, NCBI: NP_001014431.1, UniProt: P31749 |
Catalog # | MBS8538198 |
Price | $280 |
Order / More Info | AKT (Pan) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |