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Antigenic Specificity | Calreticulin |
Clone | [1G6A7] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium. |
Immunogen | Immunogen: Calreticulin antibody was raised in Mouse using synthetic peptide corresponding to aa (EEEDVPGQAKDELC) of human Calreticulin, conjugated to KLH as the immunogen. |
Other Names | [Mouse Calreticulin; Calreticulin; Calreticulin; cC1qR; CRT; FLJ26680; RO; SSA; Autoprotein RO; CALR; CALR protein; Calregulin; CRP55; CRTC; ERp60; FLJ26680; grp60; HACBP; Sicca syndrome protein A] |
Gene, Accession # | [CRT], Gene ID: 811, NCBI: NP_004334.1, UniProt: P27797 |
Catalog # | MBS5310891 |
Price | $460 |
Order / More Info | Calreticulin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |