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Antigenic Specificity | LGR5/GPR49 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. |
Immunogen | Immunogen: A synthesized peptide derived from human LGR5/GPR49 |
Other Names | [FEX; GPR49; GPR67; GRP49; LGR5; HG38; 8] |
Gene, Accession # | [LGR5/GPR49], Gene ID: 8549, NCBI: NP_001264155.1, UniProt: O75473 |
Catalog # | MBS8542438 |
Price | $280 |
Order / More Info | LGR5/GPR49 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |