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Antigenic Specificity | ILP-2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax |
Immunogen | Immunogen Type: Peptide Immunogen Description: ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2. |
Other Names | [baculoviral IAP repeat-containing protein 8; Baculoviral IAP repeat-containing protein 8; baculoviral IAP repeat-containing protein 8; baculoviral IAP repeat containing 8; Inhibitor of apoptosis-like protein 2; IAP-like protein 2; ILP-2; Testis-specific inhibitor of apoptosis] |
Gene, Accession # | [ILP-2], Gene ID: 112401, NCBI: NP_203127 |
Catalog # | MBS9401382 |
Price | $320 |
Order / More Info | ILP-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |