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Antigenic Specificity | TLR6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cat, human, mouse, rat, porcine |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | 0.78-0.80 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FITC-Conjugated Toll-like receptor 6 AntibodyParticipates in the innate immune response to Gram-positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Recognizes mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor (STF), phenol-soluble modulin (PSM) and B.burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 195-225 on human TLR6 protein. Expression: Detected in monocytes, CD11c immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. |
Other Names | [CD286; TLR 6; Toll like receptor 6 precursor] |
Gene, Accession # | [TLR6], Gene ID: 10333, NCBI: Q9Y2C9.2, UniProt: Q9Y2C9 |
Catalog # | MBS5400098 |
Price | $495 |
Order / More Info | TLR6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |