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Antigenic Specificity | MED18 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MED18 protein. Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Furumoto T., Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.Gregory S.G., Nature 441:315-321(2006). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human MED18. |
Other Names | [FLJ20045; mediator 18; mediator of RNA polymerase II transcription 18; p28b] |
Gene, Accession # | [MED18], Gene ID: 54797, NCBI: NP_001120822.1, UniProt: Q9BUE0 |
Catalog # | MBS9411995 |
Price | $200, $255 |
Order / More Info | MED18 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |