Human Angiopoietin-2 / Ang-2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human Angiopoietin-2 / Ang-2 |
| Clone | [1F29] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2 |
| Format | Protein G purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) - Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes human Ang-2 in western blot without cross reactivity with human Ang-1. Reactivity to Ang-2 of other species is not tested. Angiopoietin2 (Ang2I3/4 also ANGPT2) is a secreted glycoprotein that plays a complex role in angiogenesis and inflammation. Mature Ang2 is 478 amino acids (aa) in length. It contains one coiledcoil domain (aa 166-248) that mediates multimerization, and a C-terminal fibrinogen like domain (aa 275-495) that mediates receptor binding. Under reducing conditions, secreted monomeric Ang2 is 65-66 kDa in size. Under nonreducing conditions, both natural and recombinant Ang2 form 140 kDa dimers, 200 kDa trimers, and 250-300 kDa tetramers and pentamers. Alternate splicing generates a short isoform that lack |
| Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with purified human recombinant human Angiopoietin-2). The IgG2 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography. Antigen: recombinant human Angiopoietin-2 |
| Other Names | [human Angiopoietin-2], [VCAN; VCAN; WGN; ERVR; GHAP; PG-M; WGN1; CSPG2; CSPG2; Chondroitin sulfate proteoglycan 2; GHAP] |
| Gene, Accession # | [Ang-2], Gene ID: 1462, NCBI: NP_001119808.1, UniProt: Q15123 |
| Catalog # | MBS690265 |
| Price | $490 |
| Order / More Info | Human Angiopoietin-2 / Ang-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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