cIAP-2 / HIAP-1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | cIAP-2 / HIAP-1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg |
| Concentration | 0.2 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: Apoptosis can be inhibited by a group of proteins called inhibitors of apoptosis (IAPs). These proteins contain a BIR (baculovirus IAP repeat) domain near the amino-terminus. The BIR domain can bind some caspases. Many members of the IAP family of proteins block proteolytic activation of caspase-3 and -7. For example, XIAP, cIAP-1 and cIAP-2 appear to block cytochrome c-induced activation of caspase-9, thereby preventing initiation of the caspase cascade. Since cIAP-1 and cIAP-2 were first identified as components in the cytosolic death domain-induced complex associated with the TNF family of receptors, they may inhibit apoptosis by additional mechanisms. |
| Immunogen | Immunogen: Synthetic peptide surrounding amino acid 510 of human cIAP-2 |
| Other Names | [CIAP2; cIAP2; IAP1; AIP1; HIAP-1; HIAP1; API2; C-IAP2; hiap-1; HAIP1; MIHC; MALT2; BIRC3], [BIRC3; BIRC3; AIP1; API2; MIHC; CIAP2; HAIP1; HIAP1; MALT2; RNF49; c-IAP2; API2; IAP1; MIHC; RNF49; API2; IAP-1; hIAP-1; hIAP1] |
| Gene, Accession # | [cIAP-2/HIAP-1], Gene ID: 330, NCBI: NP_001156.1, UniProt: Q13489 |
| Catalog # | MBS840501 |
| Price | $150, $290 |
| Order / More Info | cIAP-2 / HIAP-1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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