R MKP3 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | R MKP3 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Rat MKP3 antibody is generated from rabbits immunized with a 6xHIS-tagged recombinant protein encoding aa 1~381 of rat MKP3. Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36% identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis |
| Immunogen | n/a |
| Other Names | [Dual specificity protein phosphatase 6; Mitogen-activated protein kinase phosphatase 3; MAP kinase phosphatase 3; MKP-3; Dusp6; Mkp3] |
| Gene, Accession # | [Dusp6], Gene ID: 116663, NCBI: NP_446335.1, UniProt: Q64346 |
| Catalog # | MBS9214713 |
| Price | $165, $370 |
| Order / More Info | R MKP3 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Muda,M., et al. J. Biol. Chem. 271 (8), 4319-4326 (1996) Mourey,R.J., et al. J. Biol. Chem. 271 (7), 3795-3802 (1996) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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