STUB1 (C-term) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | STUB1 (C-term) |
| Clone | [1008CT12.4.1] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1,k |
| Format | unconjugated |
| Size | 0.05 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This STUB1 antibody is generated from a mouse immunized with a recombinant protein of human STUB1. E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Collaborates with ATXN3 in the degradation of misfolded chaperone substrates: ATXN3 restricting the length of ubiquitin chain attached to STUB1/CHIP substrates and preventing further chain extension. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. Mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. Mediates polyubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', t |
| Immunogen | n/a |
| Other Names | [E3 ubiquitin-protein ligase CHIP; 6.3.2.-; Antigen NY-CO-7; CLL-associated antigen KW-8; Carboxy terminus of Hsp70-interacting protein; STIP1 homology and U box-containing protein 1 {ECO:0000312|HGNC:HGNC:11427}; STUB1 (HGNC:11427)] |
| Gene, Accession # | [STUB1], Gene ID: 10273, NCBI: NP_001280126.1, UniProt: Q9UNE7 |
| Catalog # | MBS9230982 |
| Price | $165, $370 |
| Order / More Info | STUB1 (C-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Scanlan M.J.,et al.Int. J. Cancer 76:652-658 (1998). Ballinger C.A.,et al.Mol. Cell. Biol. 19:4535-4545 (1999). Krackhardt A.M.,et al.Blood 100:2123-2131 (2002). Daniels R.J.,et al.Hum. Mol. Genet. 10:339-352 (2001). Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729 (2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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