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Antigenic Specificity | DOK1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | horse, human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against DOK1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chr |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DOK1 |
Other Names | [docking protein 1 isoform a; Docking protein 1; docking protein 1; docking protein 1; Downstream of tyrosine kinase 1; p62(dok); pp62] |
Gene, Accession # | [DOK1], Gene ID: 1796, NCBI: NP_001372, UniProt: Q99704 |
Catalog # | MBS3224425 |
Price | $335 |
Order / More Info | DOK1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |