DOK1 - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDOK1 - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshorse, human
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against DOK1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: DOK1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. DOK1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chr
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DOK1
Other Names[docking protein 1 isoform a; Docking protein 1; docking protein 1; docking protein 1; Downstream of tyrosine kinase 1; p62(dok); pp62]
Gene, Accession #[DOK1], Gene ID: 1796, NCBI: NP_001372, UniProt: Q99704
Catalog #MBS3224425
Price$335
Order / More InfoDOK1 - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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