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Antigenic Specificity | SOCS2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOCS2 is a protein that in humans is encoded by the SOCS2 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signalling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon-gamma (IFN-gamma). The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor 1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. |
Immunogen | Immunogen: SOCS2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human SOCS2, identical to the related Rabbit and rat sequence as the immunogen |
Other Names | [Affinity Purified Rabbit SOCS2; SOCS2; SOCS2; Suppressor of cytokine signaling 2; SOCS-2; SOCS2; SOCS-2; SOCS 2; SOCS 2] |
Gene, Accession # | [SOCS2], Gene ID: 8835, UniProt: O14508 |
Catalog # | MBS5312711 |
Price | $345 |
Order / More Info | SOCS2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |