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Antigenic Specificity | ITGAV |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324). ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:19578119). ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) whi |
Immunogen | Immunogen: Recombinant Human Integrin alpha-V protein (775-885AA) |
Other Names | [Integrin alpha-V; Vitronectin receptor subunit alpha; CD_antigen: CD51; Integrin alpha-V heavy chain; Integrin alpha-V light chain; ITGAV; MSK8; VNRA] |
Gene, Accession # | [ITGAV], Gene ID: 3685, NCBI: NP_001138471.1, UniProt: P06756 |
Catalog # | MBS7104949 |
Price | $160, $235 |
Order / More Info | ITGAV Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |