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Antigenic Specificity | LYK5 (C-term), 364-393 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This LYK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 364-393 amino acids from the C-terminal region of human LYK5. LYK5, also STE20-related Adaptor Protein (STRAD) are members of STE-20 like kinase family that are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. STRAD-LKB1 interaction |
Immunogen | n/a |
Other Names | [STE20-related kinase adapter protein alpha; STRAD alpha; STE20-related adapter protein; Serologically defined breast cancer antigen NY-BR-96; STRADA; LYK5 {ECO:0000312|EMBL:AAP422801}; STRAD] |
Gene, Accession # | [STRADA], Gene ID: 92335, NCBI: NP_001003786.1, UniProt: Q7RTN6 |
Catalog # | MBS9208688 |
Price | $165, $370 |
Order / More Info | LYK5 (C-term), 364-393 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |