Robo2 (C-Terminal Region) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityRobo2 (C-Terminal Region)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse, chicken
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis antibody was affinity purified using Robo2 (C-terminal region) peptide. The purified antibody detects a 175 kDa* band corresponding to Robo2 in Western blots of mouse C2C12 and SYF cells. The Robo family of repulsive guidance receptors (Robo1-4) have important roles in controlling axon guidance and cell migration. These receptors are members of the immunoglobulin (Ig) superfamily and consist of an ectodomain with five Ig domains and three fibronectin type III repeats, a single transmembrane domain, and a long cytoplasmic tail that contains four blocks of conserved cytoplasmic sequences. In Drosophila, mutations in Robo, and its midline-expressed ligand Slit, result in too many axons crossing and staying at the midline. Several proteins
ImmunogenImmunogen: Robo2 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human Robo2. This sequence has significant homology to the same region in rat and mouse Robo2, and has low homology to other Robo family members.
Other Names[roundabout2], [ROBO2; ROBO2; SAX3; KIAA1568]
Gene, Accession #[Robo2], Gene ID: 6092, NCBI: NP_001122401.1, UniProt: Q9HCK4
Catalog #MBS474135
Price$325
Order / More InfoRobo2 (C-Terminal Region) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKidd, T. et al. (1998) Cell 92:205.Bashaw, G.J. et al. (2000). Cell 101:703.Yang, L. & Bashaw, G.J. (2006). Neuron 52:595.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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