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Antigenic Specificity | Robo2 (C-Terminal Region) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse, chicken |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was affinity purified using Robo2 (C-terminal region) peptide. The purified antibody detects a 175 kDa* band corresponding to Robo2 in Western blots of mouse C2C12 and SYF cells. The Robo family of repulsive guidance receptors (Robo1-4) have important roles in controlling axon guidance and cell migration. These receptors are members of the immunoglobulin (Ig) superfamily and consist of an ectodomain with five Ig domains and three fibronectin type III repeats, a single transmembrane domain, and a long cytoplasmic tail that contains four blocks of conserved cytoplasmic sequences. In Drosophila, mutations in Robo, and its midline-expressed ligand Slit, result in too many axons crossing and staying at the midline. Several proteins |
Immunogen | Immunogen: Robo2 synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminal region of human Robo2. This sequence has significant homology to the same region in rat and mouse Robo2, and has low homology to other Robo family members. |
Other Names | [roundabout2], [ROBO2; ROBO2; SAX3; KIAA1568] |
Gene, Accession # | [Robo2], Gene ID: 6092, NCBI: NP_001122401.1, UniProt: Q9HCK4 |
Catalog # | MBS474135 |
Price | $325 |
Order / More Info | Robo2 (C-Terminal Region) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kidd, T. et al. (1998) Cell 92:205.Bashaw, G.J. et al. (2000). Cell 101:703.Yang, L. & Bashaw, G.J. (2006). Neuron 52:595. |