Occludin (OCLN) (Tight Junctions Marker) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Occludin (OCLN) (Tight Junctions Marker) |
| Clone | [OCLN/2183] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of Occludin. Expression of Occludin is upregulated by polyunsaturated fatty acids, increasing trans-endothelial cell resistance and reducing cellular permeability to large molecules. The level of Occludin varies greatly depending on tissue; in brain tissue, Occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial Occludin may play a role in en |
| Immunogen | Immunogen: Recombinant human Occludin fragment around aa 282-415 (Exact sequence is proprietary) |
| Other Names | [BLCPMG; Occludin; OCLN; Phosphatase 1 regulatory subunit 115; PPP1R115; PTORCH1; Tight junction protein occludin] |
| Gene, Accession # | [OCLN], Gene ID: 100506658, NCBI: NP_001192184.1, UniProt: Q16625 |
| Catalog # | MBS4380767 |
| Price | $190, $340, $340 |
| Order / More Info | Occludin (OCLN) (Tight Junctions Marker) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Furuse, M., et al. 1993. Occludin: a novel integral membrane protein localizing at tight junctions. J. Cell Biol. 123: 1777-1788 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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