Edit |   |
---|---|
Antigenic Specificity | MYOC |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Secreted glycoprotein regulating the activation of different signaling pathways in adjacent cells to control different processes including cell adhesion, cell-matrix adhesion, cytoskeleton organization and cell migration. Promotes substrate adhesion, spreading and formation of focal contacts. Negatively regulates cell-matrix adhesion and stress fiber assembly through Rho protein signal transduction. Modulates the organization of actin cytoskeleton by stimulating the formation of stress fibers through interactions with components of Wnt signaling pathways. Promotes cell migration through activation of PTK2 and the downstream phosphatidylinositol 3-kinase signaling. Plays a role in bone formation and promotes osteoblast differentiation in a d |
Immunogen | Immunogen: Recombinant Human Myocilin protein (183-294AA) |
Other Names | [Myocilin; Myocilin 55 kDa subunit; Trabecular meshwork-induced glucocorticoid response protein1; MYOC; GLC1A; TIGR1 Publication] |
Gene, Accession # | [MYOC], Gene ID: 4653, NCBI: NP_000252.1, UniProt: Q99972 |
Catalog # | MBS7106237 |
Price | $160, $235 |
Order / More Info | MYOC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |