RIPK2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | RIPK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | bovine, human, porcine, monkey |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 0.55 ug/ul in antibody stabilization buffer |
| Applications | ELISA (EIA), IMM, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Affinity Purified Receptor-interacting Serine/Threonine-protein kinase 2 Antibody. Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. Contributes to the tyrosine phosphorylation of the guanine exchange factor ARHGEF2 through Src tyrosine kinase leading to NF-kappaB activation by NOD2. Once recruited, RIPK2 autophosphorylates and undergoes 'Lys-63'-linked polyubiquitination by E3 ubiquitin ligases XIAP, BIRC2 and BIRC3. The polyubiquitinated protein mediates the recruitment of MAP3K7/TAK1 to IKBKG/NEMO and induces 'Lys-63'-linked polyubiquitinatio |
| Immunogen | Immunogen: Synthetic peptide taken within amino acid region 410-460 on human RIPK2 protein. Expression: Detected in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node. |
| Other Names | [CARD carrying kinase; CARD CONTAINING ICE ASSOCIATED KINASE; CARD containing interleukin 1 beta converting enzyme associated kinase; CARDIAK; CLARP kinase; GIG 30; Growth inhibiting gene 30; Receptor interacting protein 2; Receptor interacting serine threonine kinase 2; RICK; RIP-like-interacting CLARP kinase], [RIPK2; RIPK2; CCK; RICK; RIP2; CARD3; GIG30; CARDIAK; CARDIAK; RICK; RIP2; CARD-containing IL-1 beta ICE-kinase; RIP-2] |
| Gene, Accession # | [RIPK2], Gene ID: 8767, NCBI: AAQ89173.1, UniProt: O43353 |
| Catalog # | MBS540791 |
| Price | $390 |
| Order / More Info | RIPK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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