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Antigenic Specificity | EMP2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progressio |
Immunogen | Immunogen: A synthetic peptide of human EMP2 (NP 001415.1). |
Other Names | [epithelial membrane protein 2; Epithelial membrane protein 2; epithelial membrane protein 2; epithelial membrane protein 2; Protein XMP] |
Gene, Accession # | [EMP2], Gene ID: 2013, NCBI: NP_001415.1, UniProt: P54851 |
Catalog # | MBS8570988 |
Price | $280 |
Order / More Info | EMP2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |