PIWIL2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPIWIL2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration0.7 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total PIWIL2 protein. PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. Indirectly modulate expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Inhibits tumor cell growth when repressed. When overexp
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human piwi-like 2 (Drosophila)
Other Names[CT80; HILI; mili; PIWIL1L]
Gene, Accession #[PIWIL2], Gene ID: 55124, NCBI: NP_001129193.1, UniProt: Q8TC59
Catalog #MBS9404060
Price$255
Order / More InfoPIWIL2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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