UFD1L Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | UFD1L |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: UFD1L antibody detects endogenous levels of UFD1L. Function: Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. It may be involved in the development of some ectoderm-derived structures (By similarity). Acts as a negative regulator of type I interferon production via the complex formed with VCP and NPLOC4, which binds to DDX |
| Immunogen | Immunogen: A synthesized peptide derived from human UFD1L. Subcellular Location: Nucleus. Cytoplasm > Cytosol. Tissue Specificity: Found in adult heart, skeletal muscle and pancreas, and in fetal liver and kidney. Predicted Cross Reactivity: Pig, Horse, Rabbit, Dog, Chicken Similarity: Pig (100%), Horse (100%), Rabbit (92%), Dog (100%), Chicken (100%) |
| Other Names | [UB fusion protein 1; Ubiquitin fusion degradation 1 like (yeast); Ubiquitin fusion degradation 1 like; Ubiquitin fusion degradation protein 1 homolog; UFD1; UFD1_HUMAN; UFD1L] |
| Gene, Accession # | [UFD1L], Gene ID: 7353, NCBI: NP_001030324.2, UniProt: Q92890 |
| Catalog # | MBS9603722 |
| Price | $240, $280 |
| Order / More Info | UFD1L Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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