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Antigenic Specificity | Atf7ip - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, porcine, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Atf7ip. It was validated on Western BlotTarget Description: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Atf7ip can both act as an activator or a repressor depending on the context. It mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Atf7ip is required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9' (H3K9me3). The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Atf7ip |
Other Names | [activating transcription factor 7-interacting protein 1; Activating transcription factor 7-interacting protein 1; activating transcription factor 7-interacting protein 1; activating transcription factor 7 interacting protein; ATFa-associated modulator; mAM; MBD1-containing chromatin-associated factor 1] |
Gene, Accession # | [ATF7IP], Gene ID: 54343, NCBI: NP_062299, UniProt: Q7TT18 |
Catalog # | MBS3203513 |
Price | $335 |
Order / More Info | Atf7ip - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |