Human Histone deacetylase 3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Histone deacetylase 3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
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DescriptionResponsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP300 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 r
ImmunogenImmunogen: Recombinant human Histone deacetylase 3 protein(1-428aa)
Other Names[HD3; RPD3-2; SMAP45; HDAC3]
Gene, Accession #Gene ID: 8841, NCBI: NP_003874.2, UniProt: O15379
Catalog #MBS7001579
Price$160, $235
Order / More InfoHuman Histone deacetylase 3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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