GSK-3alpha Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GSK-3alpha |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes GSK-3 alpha. It reacts with human, mouse and rat. The other species are not tested. Glycogen Synthase Kinase-3 has two isoforms, GSK-3alpha and GSK3beta. GSK3 is a serine/threonine kinase that affects glycogen metabolism by phosphorylating and down-regulating the activity of muscle glycogen synthase as well as the regulation in Wnt signal pathway. GSK-3 alpha reduces the substrates beta-catenin and tau to imply an important role in Wnt signaling and tauopathies such as Alzheimer's disease. |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to N-terminus of human GSK3-alpha protein. This sequence is identical among human, mouse and rat. |
| Other Names | [Rabbit -GSK3alpha; Glycogen synthase kinase 3 alpha (GSK3a)], [GSK3A; GSK3A; DKFZp686D0638] |
| Gene, Accession # | [GSK-3 alpha], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
| Catalog # | MBS462052 |
| Price | $285 |
| Order / More Info | GSK-3alpha Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ayodeji A Ssuni, et al. GSK3alpha exhibits beta-catenin and tau directed kinase activities that are modulated by Wnt (2006). Eur J Neurosci. 24 (12): 3387-92. Yuko Kawakami, et al. Protein Kinase C _II Regulates Akt Phosphorylation on Ser-473 in a Cell Type- and Stimulus-specific Fashion (2004) THE J. Biol. Chem. 279 (46): 47720-47725. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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