Edit |   |
---|---|
Antigenic Specificity | TRIF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TRIF Antibody: TRIF is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TRIF, along with other molecules such as TIRP, TIRAP, and MyD88, serves as an adaptor protein to several of the TLR molecules. Following activation of TLR3 and TLR4, TRIF engages the kinase TBK1 and allows its subsequent activation of the interferon regulatory factor (IRF)-3. TRIF is also involved in the activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κB. |
Immunogen | Immunogen: TRIF antibody was raised against a peptide corresponding to 14 amino acids near the C-terminus of human TRIF. Buffer: TRIF Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TRIF; TRIF; IIAE6; MyD88-3; PRVTIRB; TICAM-1; TRIF; TIR domain-containing adapter molecule 1; Proline-rich; vinculin and TIR domain-containing protein B; toll-like receptor adaptor molecule 1], [TICAM1; TICAM1; TRIF; IIAE6; MyD88-3; PRVTIRB; TICAM-1; PRVTIRB; TRIF; TICAM-1; MyD88-3; TIR domain-containing adapter protein inducing IFN-beta] |
Gene, Accession # | [TICAM1], Gene ID: 148022, NCBI: NP_891549, UniProt: Q8IUC6 |
Catalog # | MBS150991 |
Price | $375 |
Order / More Info | TRIF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |