TH1L Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TH1L |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, ratpredicted: porcine, zebrafish, bovine, horse, sheep, rabbit, dog, chicken |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TH1L Antibody detects endogenous levels of TH1L. Description: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. Binds RNA which may help to stabilize the NELF complex on nucleic acid. In vitro, the NELFA:NELFCD subcomplex binds to ssDNA and ssRNA in a sequence- and structure-dependent manner.Subunit Structure: The NELF complex is composed of NELFA, NELFB, NELFCD (isoform NELF-C |
| Immunogen | Immunogen: A synthesized peptide derived from human TH1L. Tissue Specificity: Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal and cardiac muscle, adrenal, thyroid, kidney and pancreas. |
| Other Names | [HSPC130; Negative elongation factor C/D; NELF C; NELF D; NELF-C/D; NELFC; NELFD; NELFD_HUMAN; TH1; TH1-like protein; TH1L] |
| Gene, Accession # | [TH1L], Gene ID: 51497, NCBI: Q8IXH7.2, UniProt: Q8IXH7 |
| Catalog # | MBS9611522 |
| Price | $240, $280 |
| Order / More Info | TH1L Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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