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Antigenic Specificity | MCTS1 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MCTS1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: MCTS1 is an anti-oncogene that play a role in cell cycle regulation; decreases cell doubling time and anchorage-dependent growth; shortens the duration of G1 transit time and G1/S transition. When constituvely expressed, MCTS1 increases CDK4 and CDK6 kinases activity and CCND1/cyclin D1 protein level, as well as G1 cyclin/CDK complex formation. MCTS1 plays a role as translation enhancer; and recruits the density-regulated protein/DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile; MCTS1 up-regulates protein levels of BCL2L2, T |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MCTS1 |
Other Names | [malignant T-cell-amplified sequence 1 isoform 1; Malignant T-cell-amplified sequence 1; malignant T-cell-amplified sequence 1; MCTS1 re-initiation and release factor; Multiple copies T-cell malignancies] |
Gene, Accession # | [MCTS1], Gene ID: 28985, NCBI: NP_054779, UniProt: Q9ULC4 |
Catalog # | MBS3205450 |
Price | $335 |
Order / More Info | MCTS1 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |