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Antigenic Specificity | PRNP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PRNP antibody detects endogenous levels of total PRNP. Description: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found |
Immunogen | Immunogen: A synthesized peptide derived from human PRNP Subcellular Location: Cell Membrane; Lipid-Anchor; GPI-Anchor Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (92%), Rabbit (83%), Dog (100%) |
Other Names | [Alternative prion protein; major prion protein; AltPrP; ASCR; CD230; CD230 antigen; CJD; GSS; KURU; Major prion protein; p27 30; PRIO_HUMAN; Prion protein; Prion related protein; PRIP; PRNP; PrP; PrP27 30; PrP27-30; PrP33-35C; PrPC; PrPSc; Sinc] |
Gene, Accession # | [PRNP], Gene ID: 5621, NCBI: NP_000302.1, UniProt: P04156 |
Catalog # | MBS9607687 |
Price | $240, $280 |
Order / More Info | PRNP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |