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Antigenic Specificity | CHCHD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17 or MICU1 (PubMed:16185709, PubMed:26387864, PubMed:19182799, PubMed:21059946, PubMed:23186364). Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS) (PubMed:16185709, PubMed:19182799, PubMed:21059946). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria (PubMed:16185709, PubMed:19182799, PubMed:21059946). The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contains an intramolecu |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human CHCHD4 (NP 001091972.1). |
Other Names | [MIA40; TIMM40] |
Gene, Accession # | [CHCHD4], Gene ID: 131474, NCBI: NP_001091972.1, UniProt: Q8N4Q1 |
Catalog # | MBS8548845 |
Price | $280 |
Order / More Info | CHCHD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |