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Antigenic Specificity | Human HLA-DR |
Clone | [L243] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The LN3 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD alpha (heavy) chain and a 27 kD beta (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. |
Immunogen | n/a |
Other Names | [Human HLA-DR; HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain; MHC class II antigen DRA; HLA-DRA1/DRB1; DRA/DRB1] |
Gene, Accession # | [HLA-DR], Gene ID: 3122, NCBI: NP_061984.2, UniProt: P01903 |
Catalog # | MBS2553965 |
Price | $60, $70 |
Order / More Info | Human HLA-DR Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Levacher M, et al. 1990. Clin. Exp. Immunol. 81:177. 2. Terstappen L, et al. 1990. J. Leuk. Biol. 48:138. 3. Edwards J, et al. 1985. J. Immunol. 137:490. 4. van Es A, et al. 1984. Transplantation 37:65. 5. O'Doherty U, et al. 1994. Immunology 82:487. 6. Thomas R, et al. 1994. J. Immunol. 153:4016. 7. Grouard G, et al. 1996. Nature 384:364. |