PLD1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPLD1
Clonepolyclonal
Host Speciesn/a
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionDescription: Rabbit IgG polyclonal antibody for Phospholipase D1(PLD1) detection. Tested with WB in Human;Mouse. Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamm
ImmunogenImmunogen: E Coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively. Ig Type: Rabbit IgG
Other Names[Phospholipase D1; Choline phosphatase 1; hPLD 1; hPLD1; Human ARF activated phosphatidylcholine specific phospholipase D1a; Phosphatidylcholine hydrolyzing phospholipase D1; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; Phospholipase D1 phosphatidylcholine specific; PhospholipaseD1; PL D1; PLD 1; PLD1; PLD1_HUMAN; phospholipase D1, phosphatidylcholine-specific], [PLD1; PLD1; PLD 1; hPLD1]
Gene, Accession #[PLD1], Gene ID: 5337, NCBI: NP_002653.1, UniProt: Q13393
Catalog #MBS177653
Price$280
Order / More InfoPLD1 Antibody from MYBIOSOURCE INC.
Product Specific References1. Entrez Gene: PLD1 phospholipase D1, phosphatidylcholine-specific 2. Colley, W. C., Altshuller, Y. M., Sue-Ling, C. K., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Branch, K. D., Tsirka, S. E., Bollag, R. J., Bollag, W. B., Frohman, M. A. Cloning and expression analysis of murine phospholipase D1. Biochem. J. 326: 745-753, 1997. 3. Park SH, Chun YH, Ryu SH, Suh PG, Kim H (February 1999). Assignment of human PLD1 to human chromosome band 3q26 by fluorescence in situ hybridization. Cytogenet Cell Genet82 (3-4): 224.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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