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Antigenic Specificity | PLD1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Phospholipase D1(PLD1) detection. Tested with WB in Human;Mouse. Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamm |
Immunogen | Immunogen: E Coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively. Ig Type: Rabbit IgG |
Other Names | [Phospholipase D1; Choline phosphatase 1; hPLD 1; hPLD1; Human ARF activated phosphatidylcholine specific phospholipase D1a; Phosphatidylcholine hydrolyzing phospholipase D1; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; Phospholipase D1 phosphatidylcholine specific; PhospholipaseD1; PL D1; PLD 1; PLD1; PLD1_HUMAN; phospholipase D1, phosphatidylcholine-specific], [PLD1; PLD1; PLD 1; hPLD1] |
Gene, Accession # | [PLD1], Gene ID: 5337, NCBI: NP_002653.1, UniProt: Q13393 |
Catalog # | MBS177653 |
Price | $280 |
Order / More Info | PLD1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Entrez Gene: PLD1 phospholipase D1, phosphatidylcholine-specific 2. Colley, W. C., Altshuller, Y. M., Sue-Ling, C. K., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Branch, K. D., Tsirka, S. E., Bollag, R. J., Bollag, W. B., Frohman, M. A. Cloning and expression analysis of murine phospholipase D1. Biochem. J. 326: 745-753, 1997. 3. Park SH, Chun YH, Ryu SH, Suh PG, Kim H (February 1999). Assignment of human PLD1 to human chromosome band 3q26 by fluorescence in situ hybridization. Cytogenet Cell Genet82 (3-4): 224. |