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Antigenic Specificity | Phospho-PRKCD-T505 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Calcium-independent, phospholipid-and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Negatively regulates B cell proliferation and also has an important function in self-antigen induced B cell tolerance induction. Upon DNA damage, activates the promoter of the death-promoting transcription factor |
Immunogen | Immunogen: A synthetic phosphorylated peptide around T505 of human PRKCD (NP 006245.2). |
Other Names | [MAY1; PKCD; ALPS3; CVID9; nPKC-delta] |
Gene, Accession # | [PRKCD], Gene ID: 5580, NCBI: NP_006245.2, UniProt: Q05655 |
Catalog # | MBS8550682 |
Price | $280 |
Order / More Info | Phospho-PRKCD-T505 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |