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Antigenic Specificity | SNCA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SNCA, also named as NACP, PARK1 and Alpha-synuclein, belongs to the synuclein family. It may be involved in the regulation of dopamine release and transport. SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. The deposition of aggregated SNCa is the pathological hallmark of Lewy body disease, which includes Parkinson's disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer's disease (LBV).(PMID:21056999) This antibody can recognize all the isoforms of SNCA. |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [alpha-Synuclein: a-Synuclein; TLR7-like], [SNCA; SNCA; PD1; NACP; PARK1; PARK4; NACP; PARK1; NACP] |
Gene, Accession # | [SNCA], Gene ID: 6622, NCBI: P37840.1, UniProt: P37840 |
Catalog # | MBS125846 |
Price | $275, $430 |
Order / More Info | SNCA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |