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Antigenic Specificity | Neuron-specific class III beta-tubulin |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to the near of N-terminal residues of neuro-specific class III beta-tubulin. Tubulin is a compound of subunits of A tubulin and B tubulin. Class III beta tubulin (beta III-tubulin) is a vertebrate tubulin isotype specific to the neurons and mammalian testis cells, making it an ideal neuronal marker. Overexpression of class III beta tubulin is associated with the resistances of microtubule-targeted cancer drugs in lung cancer cell lines, breast cancer cell lines, and ovarian tumors. |
Immunogen | n/a |
Other Names | [tubulin beta-3 chain isoform 2; Tubulin beta-3 chain; tubulin beta-3 chain; tubulin beta 3 class III; Tubulin beta-4 chain; Tubulin beta-III], [TUBB3; TUBB3; CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A; TUBB4] |
Gene, Accession # | Gene ID: 10381, NCBI: NP_001184110.1, UniProt: Q13509 |
Catalog # | MBS850425 |
Price | $280 |
Order / More Info | Neuron-specific class III beta-tubulin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Wang, HW et al. Nature 435: 911-915, 2005. 2. Cleveland, DW et al. Cell 20: 95-105, 1980. 3. Hasegawa S et al. Clin Can Res 9: 2992-2997, 2003. |