Phospho-Thr34 DARPP-32 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-Thr34 DARPP-32 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Specific for the ~32k DARPP-32 protein phosphorylated at Thr34. Immunolabeling is blocked by lambda-phosphatase treatment. Affinity purified rabbit polyclonal antibody |
| Immunogen | Antigen: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr34 of rat DARPP-32. Immunogen Information: Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr34 conjugated to KLH. Immunogen Species: Rat |
| Other Names | [protein phosphatase 1 regulatory subunit 1B; Protein phosphatase 1 regulatory subunit 1B; protein phosphatase 1 regulatory subunit 1B; neuronal phosphoprotein DARPP-32; dopamine- and cAMP-regulated neuronal phosphoprotein; dopamine- and cAMP-regulated phosphoprotein DARPP-32; protein phosphatase 1, regulatory (inhibitor) subunit 1B; DARPP-32; Dopamine- and cAMP-regulated neuronal phosphoprotein], [Ppp1r1b; Ppp1r1b; Darpp32; Darpp-32] |
| Gene, Accession # | [PPP1R1B], Gene ID: 360616, NCBI: NP_612530.1, UniProt: Q6J4I0 |
| Catalog # | MBS502018 |
| Price | $360 |
| Order / More Info | Phospho-Thr34 DARPP-32 Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ, Huganir RL, Hemmings HC, Jr., Nairn AC, Greengard P (1999) Phosphorylation of DARPP-32 by cdk5 modulates dopamine signalling in neurons. Nature (London) 402:669-671.• Fienberg, A.A., Hiroi, N., Mermelstein, P.G., Song, W., Snyder, G.L., Nishi, A., Cheramy, A. O'Callaghan, J.P., Miller, D.B., Cole, D.G., Corbett, R., Haile, C.N., Cooper, D,C., Onn, S.P., Grace, A.A., Ouimet, C.C., White, F.G., Hyman, S.E., Surmeier, D.G., Girault, J., Nestler, E.J. and Greengard, P. (1998) DARPP-32: regulator of the efficacy of dopaminergic neurotransmission. Science 281:838-842.• Lindskog M, Svenningsson P, Pozzi L, Kim Y, Fienberg AA, Bibb JA, Fredholm BB, Nairn AC, Greengard P, Fisone G (2002) Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine. Nature (London) 418:774-778.• Maldve RE, Zhang TA, Ferrani-Kile K, Schreiber SS, Lippmann MJ, Snyder GL, Feinberg AA, Leslie SW, Gonzales RA, Morrisett RA (2002) DARPP-32 and the regulation of the ethanol sensitivity of NMDA receptors in the nucleus accumbens. Nature Neurosci 5:641-648.• Svenningsson P, Tzavara ET, Witkin JM, Fienberg AA, Nomikos GG, Greengard P (2002) Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac). Proc Natl Acad Sci USA 99:3182-3187. |
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MYBIOSOURCE INC.
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