CTNND2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCTNND2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: CTNND2 antibody detects endogenous levels of total CTNND2. Function: Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:25807484). Involved in the regulation of Wnt signaling (PubMed:25807484). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity). Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.Subunit Structure: Binds to E-cadherin at a juxtamembrane site within the cytoplasmic domain (By similar
ImmunogenImmunogen: A synthesized peptide derived from human CTNND2 Subcellular Location: Nucleus. Cell Junction > Adherens Junction. Tissue Specificity: Expressed in brain; highest expression is observed in fetal brain (PubMed:25807484). Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%)
Other Names[ARM-repeat protein; Catenin (cadherin associated protein) delta 2; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein); Catenin delta 2; Catenin delta-2; CTND2_HUMAN; CTNND 2; Ctnnd2; Delta catenin; Delta-catenin; GT 24; GT24; Neural plakophilin related arm repeat protein; Neural plakophilin related armadillo repeat protein; Neural plakophilin-related ARM-repeat protein; Neural plakophilin-related, Neurojungin; Neurojungin; NPRAP; T cell delta catenin]
Gene, Accession #[CTNND2], Gene ID: 1501, NCBI: NP_001275644.1, UniProt: Q9UQB3
Catalog #MBS9609665
Price$240, $280
Order / More InfoCTNND2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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