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Antigenic Specificity | CTNND2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CTNND2 antibody detects endogenous levels of total CTNND2. Function: Has a critical role in neuronal development, particularly in the formation and/or maintenance of dendritic spines and synapses (PubMed:25807484). Involved in the regulation of Wnt signaling (PubMed:25807484). It probably acts on beta-catenin turnover, facilitating beta-catenin interaction with GSK3B, phosphorylation, ubiquitination and degradation (By similarity). Functions as a transcriptional activator when bound to ZBTB33 (By similarity). May be involved in neuronal cell adhesion and tissue morphogenesis and integrity by regulating adhesion molecules.Subunit Structure: Binds to E-cadherin at a juxtamembrane site within the cytoplasmic domain (By similar |
Immunogen | Immunogen: A synthesized peptide derived from human CTNND2 Subcellular Location: Nucleus. Cell Junction > Adherens Junction. Tissue Specificity: Expressed in brain; highest expression is observed in fetal brain (PubMed:25807484). Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%) |
Other Names | [ARM-repeat protein; Catenin (cadherin associated protein) delta 2; catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein); Catenin delta 2; Catenin delta-2; CTND2_HUMAN; CTNND 2; Ctnnd2; Delta catenin; Delta-catenin; GT 24; GT24; Neural plakophilin related arm repeat protein; Neural plakophilin related armadillo repeat protein; Neural plakophilin-related ARM-repeat protein; Neural plakophilin-related, Neurojungin; Neurojungin; NPRAP; T cell delta catenin] |
Gene, Accession # | [CTNND2], Gene ID: 1501, NCBI: NP_001275644.1, UniProt: Q9UQB3 |
Catalog # | MBS9609665 |
Price | $240, $280 |
Order / More Info | CTNND2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |