Edit |   |
Antigenic Specificity | CXCR4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CXCR4 Antibody is predicted to not cross-react with other CXCR familiy members. CXCR4 Antibody: Human immunodeficiency virus (HIV) and related viruses require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CXCR4 (fusin, LESTR or HUMSTR) is a principal coreceptor for T-cell tropic strains of HIV-1 fusion and entry of human white blood cells. CXCR4 is also required for the infection by dual-tropic strains of HIV-1 and mediates CD-4 independent infection by HIV-2. The a-chemokine SDF-1 is the ligand |
Immunogen | Immunogen: CXCR4 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human CXCR4. Buffer: CXCR4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E; chemokine (C-X-C motif) receptor 4], [CXCR4; CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; HSY3RR; NPYY3R; D2S201E; CXC-R4; CXCR-4; LESTR; LAP-3; LPS-associated protein 3; SDF-1 receptor] |
Gene, Accession # | [CXCR4], Gene ID: 7852, NCBI: NP_003458 |
Catalog # | MBS151360 |
Price | $375 |
Order / More Info | CXCR4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |