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Antigenic Specificity | C2CD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: C2CD3 antibody is human, mouse and rat reactive. C2CD3, a putative calcium-dependent lipid-binding protein, is an essential regulator of intracellular transduction of the Hedgehog signal (1). It is localized at the basal body of cilia, mediates calcium-dependent vesicular transport and/or recruitment of proteins and regulates cilium biogenesis by promoting the assembly of centriolar distal appendages critical for docking ciliary vesicles and recruiting other essential ciliogenic proteins (2,3). C2CD3 directly promotes centriole elongation and OFD1 acts as a negative regulator of C2CD3 (4,5). |
Immunogen | Immunogen: C2CD3 antibody was raised against an 18 amino acid peptide near the center of human C2CD3. Buffer: C2CD3 antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [C2 calcium-dependent domain containing 3; C2 domain-containing protein 3; C2 calcium-dependent domain containing 3], [C2CD3; C2CD3; OFD14] |
Gene, Accession # | [C2CD3], Gene ID: 26005, NCBI: NP_001273506, UniProt: Q4AC94 |
Catalog # | MBS153678 |
Price | $375 |
Order / More Info | C2CD3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |