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Antigenic Specificity | SOX2 (Transcription Factor) |
Clone | [SOX2/1791] |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG2b, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. |
Immunogen | Immunogen: Recombinant human SOX2 protein fragment (aa176-305) Cellular Localization: Nuclear |
Other Names | [ANOP3; Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3); SOX-2; SRY (sex determining region Y) box 2; SRY related HMG box 2; Transcription factor SOX-2; ysb] |
Gene, Accession # | [SOX2], Gene ID: 6657, NCBI: NP_003097.1, UniProt: P48431 |
Catalog # | MBS4380226 |
Price | $190, $340, $340 |
Order / More Info | SOX2 (Transcription Factor) Antibody from MYBIOSOURCE INC. |
Product Specific References | Laudet, V., Stehelin, D. and Clevers, H. 1993. Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res. 21: 2493-2501 |